A versatile multicomponent mesoporous silica nanosystem with dual antimicrobial and osteogenic effects.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.027
Abstract: In this manuscript, we propose a simple and versatile methodology to design nanosystems based on biocompatible and multicomponent mesoporous silica nanoparticles (MSNs) for infection management. This strategy relies on the combination of antibiotic molecules and… read more here.
Keywords: methodology; mesoporous silica; effect; multicomponent mesoporous ... See more keywords
A hyaluronan-based nanosystem enables combined anti-inflammation of mTOR gene silencing and pharmacotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2018.04.113
Abstract: Accompanied by overproduction of oxidants and reduction of pH, inflammation is closely related to many diseases such as cancer, atherosclerosis, and asthma. Besides chemotherapeutic agents, the potential regulative role of autophagy in inflammation is being… read more here.
Keywords: based nanosystem; inflammation; gene silencing; hyaluronan based ... See more keywords
A visual guide to gene/optothermal synergy therapy nanosystem using tungsten oxide.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.07.077
Abstract: Combination of gene therapy and photothermal therapy (PTT) has drawn much attention in cancer therapy in recent years. However, this joint treatment process lacks fluorescence imaging visualization guidance that limits its clinical applications in oncotherapy.… read more here.
Keywords: nanosystem; gene therapy; tungsten oxide; gene optothermal ... See more keywords
NIR Remote-controlled "Lock-Unlock" Nanosystem for Imaging Potassium Ions in Living Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b05820
Abstract: Despite great achievements in sensitive and selective detection of important biomolecules in living cells, it is still challenging to develop smart and controllable sensing nanodevices for cellular studies that can be activated at desired time… read more here.
Keywords: nanosystem; dsap; lock unlock; living cells ... See more keywords
Deep-Depth Imaging of Hepatic Ischemia/Reperfusion Injury Using a Carbon Monoxide-Activated Upconversion Luminescence Nanosystem.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c15960
Abstract: Exploring a chemical imaging tool for visualizing the endogenous CO biosignaling molecule is of great importance in understanding the pathophysiological functions of CO in complex biological systems. Most of the existing CO fluorescent probes show… read more here.
Keywords: depth; reperfusion; deep depth; luminescence ... See more keywords
Multifunctional Nanosystem for Synergistic Tumor Therapy Delivered by Two-Dimensional MoS2.
Sign Up to like & getrecommendations! Published in 2017 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.7b03276
Abstract: A multifunctional nanosystem based on two-dimensional molybdenum disulfide (MoS2) was developed for synergistic tumor therapy. MoS2 was stabilized with lipoic acid (LA)-modified poly(ethylene glycol) and modified with a pH-responsive charge-convertible peptide (LA-K11(DMA)). Then, a positively… read more here.
Keywords: tumor therapy; nanosystem; mos2; synergistic tumor ... See more keywords
Paper-based visual detection of silver ions and l-cysteine with a dual-emissive nanosystem of carbon quantum dots and gold nanoclusters
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Methods"
DOI: 10.1039/c8ay01044g
Abstract: Fluorescence has been extensively employed for visual detection; however, it is inconvenient for people to distinguish single-color fluorescence changes. Herein, a dual-signal ratiometric fluorescent probe of a carbon quantum dot/gold nanocluster (CQD/Au NC) nanosystem for… read more here.
Keywords: detection; fluorescence; cys; visual detection ... See more keywords
An MTH1-targeted nanosystem for enhanced PDT via improving cellular sensitivity to reactive oxygen species.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc01841c
Abstract: Herein, we developed a strategy to attack the cancer cell defense system against reactive oxygen species to improve photodynamic therapy efficacy with a Ce6@MSN@MTH1 siRNA nanosystem, which was demonstrated to improve cellular sensitivity to reactive… read more here.
Keywords: reactive oxygen; oxygen species; cellular sensitivity; sensitivity reactive ... See more keywords
Enhancing cellular morphological changes and ablation of cancer cells via the interaction of drug co-loaded magnetic nanosystems in weak rotating magnetic fields
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra01458c
Abstract: Magnetic nanoparticles have been widely used in cancer treatment for their potential magnetic functions and synergistic antitumor effect with therapeutic agents. In this work, we developed a polymeric nanosystem by co-loading the natural anticancer drug… read more here.
Keywords: enhancing cellular; drug; cancer; loaded magnetic ... See more keywords
An Ag2S@ZIF-Van nanosystem for NIR-II imaging of bacterial-induced inflammation and treatment of wound bacterial infection.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm00550f
Abstract: Bacterial diseases pose a serious threat to human health. Continued development of precise diagnostic methods and synergistic therapy techniques for combating bacteria are needed. Herein a hybrid nanosystem (Ag2S@ZIF-Van NS) was constructed by one-step self-assembly… read more here.
Keywords: imaging bacterial; ag2s zif; zif van; van ... See more keywords
ICG-loaded and 125I-labeled theranostic nanosystem for multimodality imaging-navigated phototherapy of breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01551j
Abstract: Multimodality imaging-navigated precise phototherapy has been well-established as a promising strategy for enhancing the diagnostic and therapeutic efficiency of cancer in preclinical trials. However, proper theranostic agents with adequate biosafety and biological efficacy as well… read more here.
Keywords: breast cancer; multimodality imaging; nanosystem; cancer ... See more keywords