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   Articles with "nanosystem" as a keyword



Bioinspired Sonodynamic Nano Spray Accelerates Infected Wound Healing via Targeting and Disturbing Bacterial Metabolism

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202315576

Abstract: Bacterial infections pose a major concern for the medical community, especially regarding wound healing. Traditional passive antibiotic therapies can be cytotoxic and lead to bacterial resistance, posing a continuing challenge to treat. Based on precision… read more here.

Keywords: mmsa; infected wound; wound healing; metabolism ... See more keywords

Self‐Delivered Transformable Nanosystem Capable of Enhancing Photodynamic Effectiveness and Multi‐Target Ameliorating Immunosuppression for Treatment of Breast Cancer and Lung Metastasis

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recommendations! Published in 2024 at "Advanced Functional Materials"

DOI: 10.1002/adfm.202405051

Abstract: Homogeneous distribution and adequate accumulation of photosensitizer in tumor are essential for effective photodynamic therapy (PDT). However, the intricate tumor microenvironment (TME) often poses great challenges to the deep penetration and retention of therapeutic agents… read more here.

Keywords: delivered transformable; tumor; immunosuppression; metastasis ... See more keywords

Trash into Treasure: Nano‐coating of Catheter Utilizes Urine to Deprive H2S Against Persister and Rip Biofilm Matrix

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recommendations! Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202401067

Abstract: Bacteria‐derived hydrogen sulfide (H2S) often contributes to the emergence of antibiotic‐recalcitrant bacteria, especially persister (a sub‐population of dormant bacteria), thus causing the treatment failure of Catheter‐associated urinary tract infection (CAUTI). Here, an H2S harvester nanosystem… read more here.

Keywords: catheter; nanosystem; h2s; biofilm matrix ... See more keywords

A Fused Membrane-Camouflaged Biomimetic Nanosystem for Dual-Targeted Therapy of Septic Arthritis.

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recommendations! Published in 2025 at "Small"

DOI: 10.1002/smll.202410710

Abstract: Due to the inherent aseptic and enclosed characteristics of joint cavity, septic arthritis (SA) almost inevitably leads to intractable infections and rapidly progressing complex pathological environments. Presently, SA faces not only the deficient effectiveness of… read more here.

Keywords: septic arthritis; fused membrane; nanosystem; therapy ... See more keywords

A versatile multicomponent mesoporous silica nanosystem with dual antimicrobial and osteogenic effects.

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recommendations! Published in 2021 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2021.09.027

Abstract: In this manuscript, we propose a simple and versatile methodology to design nanosystems based on biocompatible and multicomponent mesoporous silica nanoparticles (MSNs) for infection management. This strategy relies on the combination of antibiotic molecules and… read more here.

Keywords: methodology; mesoporous silica; effect; multicomponent mesoporous ... See more keywords

A hyaluronan-based nanosystem enables combined anti-inflammation of mTOR gene silencing and pharmacotherapy.

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recommendations! Published in 2018 at "Carbohydrate polymers"

DOI: 10.1016/j.carbpol.2018.04.113

Abstract: Accompanied by overproduction of oxidants and reduction of pH, inflammation is closely related to many diseases such as cancer, atherosclerosis, and asthma. Besides chemotherapeutic agents, the potential regulative role of autophagy in inflammation is being… read more here.

Keywords: based nanosystem; inflammation; gene silencing; hyaluronan based ... See more keywords

A visual guide to gene/optothermal synergy therapy nanosystem using tungsten oxide.

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recommendations! Published in 2017 at "Journal of colloid and interface science"

DOI: 10.1016/j.jcis.2017.07.077

Abstract: Combination of gene therapy and photothermal therapy (PTT) has drawn much attention in cancer therapy in recent years. However, this joint treatment process lacks fluorescence imaging visualization guidance that limits its clinical applications in oncotherapy.… read more here.

Keywords: nanosystem; gene therapy; tungsten oxide; gene optothermal ... See more keywords

NIR Remote-controlled "Lock-Unlock" Nanosystem for Imaging Potassium Ions in Living Cells.

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recommendations! Published in 2020 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.9b05820

Abstract: Despite great achievements in sensitive and selective detection of important biomolecules in living cells, it is still challenging to develop smart and controllable sensing nanodevices for cellular studies that can be activated at desired time… read more here.

Keywords: nanosystem; dsap; lock unlock; living cells ... See more keywords

Deep-Depth Imaging of Hepatic Ischemia/Reperfusion Injury Using a Carbon Monoxide-Activated Upconversion Luminescence Nanosystem.

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recommendations! Published in 2022 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.2c15960

Abstract: Exploring a chemical imaging tool for visualizing the endogenous CO biosignaling molecule is of great importance in understanding the pathophysiological functions of CO in complex biological systems. Most of the existing CO fluorescent probes show… read more here.

Keywords: depth; reperfusion; deep depth; luminescence ... See more keywords

Multifunctional Nanosystem for Synergistic Tumor Therapy Delivered by Two-Dimensional MoS2.

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recommendations! Published in 2017 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.7b03276

Abstract: A multifunctional nanosystem based on two-dimensional molybdenum disulfide (MoS2) was developed for synergistic tumor therapy. MoS2 was stabilized with lipoic acid (LA)-modified poly(ethylene glycol) and modified with a pH-responsive charge-convertible peptide (LA-K11(DMA)). Then, a positively… read more here.

Keywords: tumor therapy; nanosystem; mos2; synergistic tumor ... See more keywords

Intelligent DNA Nanosystem for Broad-Spectrum Oncological Typing and Therapy.

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recommendations! Published in 2024 at "ACS sensors"

DOI: 10.1021/acssensors.4c02246

Abstract: The occurrence of multiple primary cancers in individual patients underscores the need for diagnostic and therapeutic techniques with augmented cancer-targeting selectivity and broad-spectrum antitumor effects. To address this, we develop a quadruple-input-triggered OR-AND-AND logic gated… read more here.

Keywords: broad spectrum; cancer; therapy; logic ... See more keywords