A Fluorinated Supramolecular Self‐Assembled Peptide as Nanovaccine Adjuvant for Enhanced Cancer Vaccine Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Small Methods"
DOI: 10.1002/smtd.202201409
Abstract: Adjuvants play an important role in enhancing vaccine‐induced immune protection. Adequate cellular uptake, robust lysosomal escape, and subsequent antigen cross‐presentation are critical steps for vaccine adjuvants to effectively elicit cellular immunity. Here, a fluorinated supramolecular… read more here.
Keywords: antigen; supramolecular self; fluorinated supramolecular; vaccine ... See more keywords
A dual-adjuvant neoantigen nanovaccine loaded with imiquimod and magnesium enhances anti-tumor immune responses of melanoma.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials science"
DOI: 10.1039/d2bm01340a
Abstract: Neoantigen-based tumor vaccines have been applied in patient-specific melanoma-derived immunogenic mutated epitopes (neoantigens), with potential antineoplastic and immunomodulating effects. Yet, their use is limited by different physicochemical properties and poor pharmacokinetics. Herein, we constructed a… read more here.
Keywords: magnesium; dual adjuvant; neoantigen nanovaccine; tumor ... See more keywords