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Formulation of co-amorphous systems from naproxen and naproxen sodium and in situ monitoring of physicochemical state changes during dissolution testing by Raman spectroscopy.

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Published in 2020 at "International journal of pharmaceutics"

DOI: 10.1016/j.ijpharm.2020.119662

Abstract: Co-amorphous systems comprising low-molecular weight drugs and co-formers constitute an interesting approach to optimize pharmaceutical performance of drugs with low aqueous solubility. Within the different types of co-amorphous systems, the combination of a drug with… read more here.

Keywords: raman; amorphous systems; sodium; situ ... See more keywords