Articles with "napabucasin plus" as a keyword



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A phase 1b study of napabucasin plus weekly paclitaxel in patients with advanced thymoma and thymic carcinoma.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.e20001

Abstract: e20001Background: Napabucasin is a first-in-class cancer stemness inhibitor, identified by its ability to inhibit STAT3-driven gene transcription and spherogenesis of cancer stem cells (Li et al PN... read more here.

Keywords: napabucasin plus; study napabucasin; paclitaxel patients; weekly paclitaxel ... See more keywords