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   Articles with "nape" as a keyword



Photoaffinity Labeling Reveals a Role for the Unusual Triply Acylated Phospholipid N-Acylphosphatidylethanolamine in Lactate Homeostasis.

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recommendations! Published in 2025 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.5c03851

Abstract: Most eukaryotic membranes comprise phospholipids bearing two hydrophobic tails, but N-acylphosphatidylethanolamine (NAPE) stands out as a long-known but poorly understood phospholipid with three hydrophobic groups. What little attention NAPE has received has been devoted to… read more here.

Keywords: photoaffinity labeling; homeostasis; lactate; nape ... See more keywords

Regiochemical Assignment of N-Acylphosphatidylethanolamines (NAPE) by Liquid Chromatography/Electrospray Ionization with Multistage Mass Spectrometry and Its Application to Extracts of Lupin Seeds.

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recommendations! Published in 2020 at "Journal of the American Society for Mass Spectrometry"

DOI: 10.1021/jasms.0c00267

Abstract: 1,2-Diacyl-sn-glycero-3-phospho-N-acyl-ethanolamines (NAPE) are low abundance phospholipids but important constituents of intracellular membranes of plant tissues, responsible for generating bioactive N-acylethanolamine (NAE), which participates in several physiological processes such as regulation of seed germination and protection… read more here.

Keywords: nape; acyl; mass spectrometry; lupin seeds ... See more keywords

Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-26826-2

Abstract: Extensive rodent literature suggests that the endocannabinoid (eCB) system present in the nucleus accumbens (NAc) modulates dopamine (DA) release in this area. However, expression patterns of the cannabinoid receptor type 1 (CB1R), the synthesizing enzyme… read more here.

Keywords: nape pld; pld faah; cb1r nape; nape ... See more keywords

20:4-NAPE induced changes of mechanical sensitivity and DRG neurons excitability are concentration dependent and mediated via NAPE-PLD

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recommendations! Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-025-98567-y

Abstract: Alterations in the excitability of dorsal root ganglion (DRG) neurons are critical in the pathogenesis of acute and chronic pain. Neurotransmitter release from the terminals of DRG neurons is regulated by cannabinoid receptor 1 (CB1)… read more here.

Keywords: drg neurons; neurons excitability; concentration; nape ... See more keywords

State of the Art Review: Thiazide diuretics exploit the endocannabinoid system via NAPE-PLD.

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recommendations! Published in 2025 at "American journal of hypertension"

DOI: 10.1093/ajh/hpaf174

Abstract: The present State of the Art Review will take stock of targeting the endocannabinoid system (ECS) in the management of hypertension and vascular diseases. Major efforts have been made in the last thirty years to… read more here.

Keywords: endocannabinoid system; state art; nape; thiazide diuretics ... See more keywords
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The role of biologic treatment in special scenarios in hidradenitis suppurativa: Facial and nape phenotype, dissecting cellulitis of the scalp, and lymphedema

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recommendations! Published in 2021 at "Dermatologic Therapy"

DOI: 10.1111/dth.14829

Abstract: Hidradenitis suppurativa (HS) is a chronic inflammatory disorder affecting the hair follicle which typically affects the axilla, inguinal, submammary, and perianal areas. Atypical HS, such as facial HS, dissecting cellulitis of the scalp (DCS), nape… read more here.

Keywords: treatment; hidradenitis suppurativa; dcs nape; cellulitis scalp ... See more keywords

Involvement of the γ Isoform of cPLA2 in the Biosynthesis of Bioactive N-Acylethanolamines

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recommendations! Published in 2021 at "Molecules"

DOI: 10.3390/molecules26175213

Abstract: Arachidonylethanolamide (anandamide) acts as an endogenous ligand of cannabinoid receptors, while other N-acylethanolamines (NAEs), such as palmitylethanolamide and oleylethanolamide, show analgesic, anti-inflammatory, and appetite-suppressing effects through other receptors. In mammalian tissues, NAEs, including anandamide, are… read more here.

Keywords: biosynthesis; cpla2; involvement isoform; isoform cpla2 ... See more keywords