Expression and localization of CB1R, NAPE-PLD, and FAAH in the vervet monkey nucleus accumbens
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DOI: 10.1038/s41598-018-26826-2
Abstract: Extensive rodent literature suggests that the endocannabinoid (eCB) system present in the nucleus accumbens (NAc) modulates dopamine (DA) release in this area. However, expression patterns of the cannabinoid receptor type 1 (CB1R), the synthesizing enzyme… read more here.
Keywords: nape pld; pld faah; cb1r nape; nape ... See more keywords
STRUCTURE-ACTIVITY RELATIONSHIP: STUDY OF LEI-401 AS INHIBITOR OF NAPE-PLD BY PHARMACOPHORE MODEL
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DOI: 10.21474/ijar01/12889
Abstract: N-acyl-phosphatidylethanolamine phospholipase D (NAPE–PLD) is considered to be the principal enzyme that produces N-acylethanolamines (NAEs), a family of signaling lipids. NAEs are involved in numerous physiological processes such as appetite, satiety, pain, inflammation, fertility, stress,… read more here.
Keywords: nape pld; pld; pharmacophore model; lei 401 ... See more keywords