Synthesis and biological activity, and molecular modelling studies of potent cytotoxic podophyllotoxin-naphthoquinone compounds
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DOI: 10.1039/d2ra03312g
Abstract: A new approach for the synthesis of podophyllotoxin-naphthoquinone compounds using microwave-assisted three-component reactions is reported in this study. Novel podophyllotoxin-naphthoquinone derivatives with modification on ring E were synthesized. All the synthetic compounds were assessed in… read more here.
Keywords: synthesis biological; podophyllotoxin; naphthoquinone compounds; biological activity ... See more keywords