Structure-Based Identification and Biological Characterization of New NAPRT Inhibitors
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DOI: 10.3390/ph15070855
Abstract: NAPRT, the rate-limiting enzyme of the Preiss–Handler NAD biosynthetic pathway, has emerged as a key biomarker for the clinical success of NAMPT inhibitors in cancer treatment. Previous studies found that high protein levels of NAPRT… read more here.
Keywords: biological characterization; structure; naprt inhibitors; based identification ... See more keywords