Narcolepsy Associated with Pandemrix Vaccine
Sign Up to like & getrecommendations! Published in 2018 at "Current Neurology and Neuroscience Reports"
DOI: 10.1007/s11910-018-0851-5
Abstract: Purpose of ReviewAfter the connection between AS03-adjuvanted pandemic H1N1 vaccine Pandemrix and narcolepsy was recognized in 2010, research on narcolepsy has been more intensive than ever before. The purpose of this review is to provide… read more here.
Keywords: pandemrix associated; disease; narcolepsy; vaccine ... See more keywords
Deep brain stimulation of hypothalamus for narcolepsy-cataplexy in mice
Sign Up to like & getrecommendations! Published in 2020 at "Brain Stimulation"
DOI: 10.1016/j.brs.2020.04.006
Abstract: BACKGROUND Narcolepsy type 1 (NT1, narcolepsy with cataplexy) is a disabling neurological disorder caused by loss of excitatory orexin neurons from the hypothalamus and is characterized by decreased motivation, sleep-wake fragmentation, intrusion of rapid-eye-movement sleep… read more here.
Keywords: cataplexy; stimulation; mice; narcolepsy ... See more keywords
Clinical Characteristics and Burden of Illness in Pediatric Patients with Narcolepsy.
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DOI: 10.1016/j.pediatrneurol.2018.06.008
Abstract: BACKGROUND Narcolepsy is a chronic and lifelong neurologic disorder with onset commonly occurring in childhood or adolescence, and affecting approximately 0.025% to 0.05% of the general population. The primary symptom is excessive daytime sleepiness, which… read more here.
Keywords: pediatric narcolepsy; characteristics burden; narcolepsy; clinical characteristics ... See more keywords
Underutilization of the MSLT in sleepy patients with a short onset REM period (SOREMP) in the sleep clinic.
Sign Up to like & getrecommendations! Published in 2017 at "Sleep medicine"
DOI: 10.1016/j.sleep.2016.11.023
Abstract: OBJECTIVE/BACKGROUND A nocturnal sleep onset REM period (defined as REM onset latency ≤ 15 min; SOREMP) occurs rarely and research has shown that the phenomenon is specific for type 1 and 2 narcolepsy. However, little is known about… read more here.
Keywords: mslt; soremp; psg soremp; onset rem ... See more keywords
Longitudinal study of narcolepsy symptoms in first, second, and third-degree relatives of simplex and multiplex narcolepsy families.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2018.06.015
Abstract: OBJECTIVE To assess the evolution of narcolepsy symptoms in first-, second, and third-degree relatives and to compare multiplex and simplex families. METHODS A total of 4045 family members and 362 narcoleptic individuals were entered in… read more here.
Keywords: degree relatives; multiplex families; first second; narcolepsy symptoms ... See more keywords
High prevalence of ADHD symptoms in unmedicated youths with post-H1N1 narcolepsy type 1.
Sign Up to like & getrecommendations! Published in 2020 at "Sleep medicine"
DOI: 10.1016/j.sleep.2020.06.014
Abstract: OBJECTIVES To characterize attention deficit-hyperactivity disorder (ADHD) symptoms in unmedicated post-H1N1 narcolepsy type 1 (NT1) youths, and explore associations between ADHD symptoms and the narcolepsy phenotype. METHODS A total of 50 consecutively enrolled post-H1N1 NT1… read more here.
Keywords: narcolepsy; adhd symptoms; adhd; post h1n1 ... See more keywords
Incidence of narcolepsy after H1N1 influenza and vaccinations: Systematic review and meta-analysis.
Sign Up to like & getrecommendations! Published in 2018 at "Sleep medicine reviews"
DOI: 10.1016/j.smrv.2017.06.006
Abstract: An increased incidence of narcolepsy was seen in many countries after the pandemic H1N1 influenza vaccination campaign in 2009-2010. The H1N1 vaccine - narcolepsy connection is based on observational studies that are prone to various… read more here.
Keywords: h1n1; risk; incidence narcolepsy; narcolepsy ... See more keywords
The Burden of Narcolepsy in Adults: A Population Sampling Study Using Personal Media.
Sign Up to like & getrecommendations! Published in 2023 at "Behavioral sleep medicine"
DOI: 10.1080/15402002.2023.2217971
Abstract: OBJECTIVE To obtain insight in the spectrum of narcolepsy symptoms and associated burden in a large cohort of patients. METHODS We used the Narcolepsy Monitor, a mobile app, to easily rate the presence and burden… read more here.
Keywords: population sampling; burden narcolepsy; narcolepsy; narcolepsy adults ... See more keywords
Changed epidemiology of narcolepsy before, during, and after the 2009 H1N1 pandemic: a nationwide narcolepsy surveillance network study in mainland China, 1990-2017.
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DOI: 10.1093/sleep/zsac325
Abstract: STUDY OBJECTIVES Increased incidence of narcolepsy was reported in children during the 2009 H1N1 pandemic following Pandemrix®, a H1N1 flu vaccine. A link with A(H1N1)pdm09 infections remains controversial. Using nationwide surveillance data from China (1990… read more here.
Keywords: incidence; h1n1 pandemic; narcolepsy; 2009 h1n1 ... See more keywords
Hypersomnia and Narcolepsy in 42 Adult Patients with Craniopharyngioma.
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DOI: 10.1093/sleep/zsad032
Abstract: STUDY OBJECTIVES To evaluate sleep, sleepiness and excessive need for sleep in patients with craniopharyngioma (a suprasellar tumor which can affect sleep-wake systems). METHODS A retrospective study of all adult craniopharyngioma patients referred to the… read more here.
Keywords: adult patients; patients craniopharyngioma; hypersomnia narcolepsy; narcolepsy ... See more keywords
0601 An Atypical Cause of Hallucinations in Type 1 Narcolepsy
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DOI: 10.1093/sleep/zsad077.0601
Abstract: Narcolepsy is a disorder of hypersomnolence affecting between 1:5000-1:10,000 individuals. Type 1 Narcolepsy can be differentiated from Type 2 Narcolepsy by the presence of cataplexy. Visual hallucinations are reported in 50-80% of T1 Narcoleptics and… read more here.
Keywords: auditory hallucinations; type narcolepsy; psychotic symptoms; narcolepsy ... See more keywords