Articles with "narcolepsy patients" as a keyword



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Risk of bone fractures in patients with narcolepsy: a nationwide population-based cohort study.

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Published in 2020 at "Sleep medicine"

DOI: 10.1016/j.sleep.2020.02.015

Abstract: OBJECTIVES Narcolepsy symptoms, such as excessive daytime sleepiness or cataplexy, can pose a risk to safety. Stimulants or antidepressants have been used to treat these symptoms. The study investigated the risk of bone fractures in… read more here.

Keywords: narcolepsy patients; risk bone; study; bone fractures ... See more keywords

Characterization of T cell receptors reactive to HCRTNH2, pHA273-287, and NP17-31 in control and narcolepsy patients

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2205797119

Abstract: Significance Amidated hypocretin peptides (HCRTNH2) are autoantigens in narcolepsy type 1, an autoimmune disorder targeting HCRT neurons. The autoimmune process can be initiated by exposure to the influenza A flu, and a particular piece of… read more here.

Keywords: reactive hcrtnh2; narcolepsy patients; characterization cell; cell receptors ... See more keywords

Morphological and Age-Related Changes in the Narcolepsy Brain.

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Published in 2021 at "Cerebral cortex"

DOI: 10.1093/cercor/bhab171

Abstract: Morphological changes in the cortex of narcolepsy patients were investigated by surface-based morphometry analysis in this study. Fifty-one type 1 narcolepsy patients and 60 demographically group-matched healthy controls provided resting-state functional and high-resolution 3T anatomical… read more here.

Keywords: narcolepsy patients; age related; increased gyrification; gyrification ... See more keywords

0584 Sodium Oxybate Treatment Patterns in Narcolepsy Patients: A Propensity Score–Matched Cohort Study Subanalysis

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Published in 2023 at "SLEEP"

DOI: 10.1093/sleep/zsad077.0584

Abstract: Sodium oxybate (SXB) is strongly recommended for treatment of narcolepsy. Patients treated with available immediate-release oxybates are required to awaken for a second dose 2.5–4 hours after the bedtime dose to cover a full night… read more here.

Keywords: second dose; oxybate; narcolepsy patients; discontinuation ... See more keywords

0457 Comparison of Radioimmunoassay and Enzyme-Linked Immunosorbent Assay for Hypocretin Detection in Cerebrospinal Fluid in Narcolepsy Patients

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Published in 2025 at "SLEEP"

DOI: 10.1093/sleep/zsaf090.0457

Abstract: Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucinations, with its pathogenesis linked to hypocretin/orexin deficiency, a key regulator of the sleep-wake cycle. This study compares the diagnostic… read more here.

Keywords: hypocretin; enzyme linked; cerebrospinal fluid; narcolepsy patients ... See more keywords

Symptom measures in pediatric narcolepsy patients: a review

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Published in 2021 at "Italian Journal of Pediatrics"

DOI: 10.1186/s13052-021-01068-7

Abstract: Purpose This study aimed to provide a summary of the measures to assess narcoleptic symptoms or complications in pediatric narcolepsy patients. Methods We searched in the National Center for Biotechnology Information (NCBI) for measures of… read more here.

Keywords: narcolepsy patients; patients review; symptom measures; frequently used ... See more keywords

Narcolepsy and the Risk of Pregnancy Complications: Based on a Nationwide Healthcare System Database in South Korea

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Published in 2025 at "European Psychiatry"

DOI: 10.1192/j.eurpsy.2025.2334

Abstract: Introduction Narcolepsy is known as an autoimmune disease which altered metabolic functions. It is believed that narcolepsy makes more pregnancy complications. However clinical evidence in narcolepsy patients, especially in pregnant women, is limited. Objectives We… read more here.

Keywords: south korea; risk; pregnancy; pregnancy complications ... See more keywords