Longitudinal study of narcolepsy symptoms in first, second, and third-degree relatives of simplex and multiplex narcolepsy families.
Sign Up to like & getrecommendations! Published in 2019 at "Sleep medicine"
DOI: 10.1016/j.sleep.2018.06.015
Abstract: OBJECTIVE To assess the evolution of narcolepsy symptoms in first-, second, and third-degree relatives and to compare multiplex and simplex families. METHODS A total of 4045 family members and 362 narcoleptic individuals were entered in… read more here.
Keywords: degree relatives; multiplex families; first second; narcolepsy symptoms ... See more keywords
Efficacy of pitolisant in patients with high burden of narcolepsy symptoms: pooled analysis of short-term, placebo-controlled studies.
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DOI: 10.1016/j.sleep.2021.02.037
Abstract: STUDY OBJECTIVE To evaluate the efficacy of pitolisant, a histamine 3 (H3)-receptor antagonist/inverse agonist, in adult patients with high burden of narcolepsy symptoms. METHODS Data were pooled from two randomized, placebo-controlled, 7- or 8-week studies… read more here.
Keywords: efficacy pitolisant; burden narcolepsy; narcolepsy symptoms; placebo ... See more keywords
Measurement of Narcolepsy Symptoms in School-Aged Children and Adolescents
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DOI: 10.1212/wnl.0000000000012272
Abstract: Objective We validated the Narcolepsy Severity Scale (NSS) in adults with narcolepsy type 1 (NT1) to quantify the severity, frequency, and consequences of the 5 key narcolepsy symptoms over the last month, and we now… read more here.
Keywords: score; narcolepsy symptoms; treatment; children adolescents ... See more keywords