Naringenin Upregulates AMPK-Mediated Autophagy to Rescue Neuronal Cells From β-Amyloid (1–42) Evoked Neurotoxicity
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01969-4
Abstract: Deposition of an amyloid-β peptide is one of the first events in the pathophysiology of Alzheimer’s disease (AD) and is clinically characterized by Aβ plaques, tau tangles, and behavioral impairments that lead to neuronal death.… read more here.
Keywords: neuronal cells; mediated autophagy; naringenin; evoked neurotoxicity ... See more keywords
Efficient biosynthesis of (2S)-naringenin from p-coumaric acid in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05218
Abstract: (2S)-Naringenin, a (2S)-flavanone, is widely used in the food, chemical, and pharmaceutical industries because of its diverse physiological activities. The production of (2S)-naringenin in microorganisms provides an ideal source that reduces the cost of the… read more here.
Keywords: saccharomyces cerevisiae; production; naringenin; naringenin coumaric ... See more keywords
Enhanced Antioxidant Effects of Naringenin Nanoparticles Synthesized using the High-Energy Ball Milling Method
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c04148
Abstract: Naringenin, one of the flavonoid components, is majorly found in and obtained from grapefruits and oranges. Naringenin also acts as a potent antioxidant, which possesses hypolipidemic as well as anti-inflammatory potential. Naringenin reduces the expressions… read more here.
Keywords: high energy; naringenin; naringenin nanoparticles; ball milling ... See more keywords
Voltammetric analysis of naringenin at a disposable pencil graphite electrode - application to polyphenol content determination in citrus juice.
Sign Up to like & getrecommendations! Published in 2018 at "Analytical Methods"
DOI: 10.1039/c8ay02281j
Abstract: The electrochemical behaviour of the flavonoid naringenin (NGN) was investigated for the first time by cyclic voltammetry (CV), using a disposable electroactivated pencil graphite electrode (PGE*). In this electrochemical sensor, NGN is irreversibly oxidized, giving… read more here.
Keywords: graphite electrode; pencil graphite; naringenin; mol ngn ... See more keywords
Naringenin biosynthesis and fabrication of naringenin mediated nano silver conjugate for antimicrobial potential.
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2022.2147931
Abstract: The development of resistance, instability and high doses are some drawbacks of biologically active natural products. Modification of natural compounds to make it broad spectrum is the standard approach in drug design. This paper sets… read more here.
Keywords: nano silver; naringenin; antimicrobial potential; silver conjugate ... See more keywords
Bacterial microbiota protect an invasive bark beetle from a pine defensive compound
Sign Up to like & getrecommendations! Published in 2018 at "Microbiome"
DOI: 10.1186/s40168-018-0518-0
Abstract: BackgroundThere is growing evidence that some devastating biotic invasions are facilitated by microbial symbionts. The red turpentine beetle (RTB), an innocuous secondary insect attacking weakened trees in North America, has formed an invasive complex with… read more here.
Keywords: degradation; microbiota; naringenin; invasive beetle ... See more keywords
Naringenin Cocrystals Prepared by Solution Crystallization Method for Improving Bioavailability and Anti-hyperlipidemia Effects
Sign Up to like & getrecommendations! Published in 2019 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-019-1324-0
Abstract: Naringenin exerts anti-inflammatory, hypolipidemic, and hepatoprotective effects; however, it shows low oral bioavailability because of poor water solubility. In this work, cocrystals of naringenin were formed to address these issues. Using the solution crystallization method,… read more here.
Keywords: solution crystallization; bioavailability; naringenin betaine; naringenin ... See more keywords
Modulation of the growth and metabolic response of cyanobacteria by the multifaceted activity of naringenin
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0177631
Abstract: The interactions between the plant-derived bioflavonoid, naringenin, and prokaryotic microalgae representatives (cyanobacteria), were investigated with respect to its influence on the growth and metabolic response of these microorganisms. To achieve reliable results, the growth of… read more here.
Keywords: growth; metabolic response; naringenin; growth metabolic ... See more keywords
Enhanced Bioavailability & higher Uptake of Brain-targeted Surface Engineered Delivery System of Naringenin developed as a therapeutic for Autism Spectrum Disorder.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug delivery"
DOI: 10.2174/1567201819666220303101506
Abstract: BACKGROUND Neuroinflammation occurring as a result of oxidative and nitrosative stress is associated with various neurological disorders and involves generation of pro-inflammatory cytokines as well as activation of microglia. Dietary phytochemicals are a safer and… read more here.
Keywords: naringenin; autism spectrum; brain; bioavailability ... See more keywords
Treatment With Naringenin Elevates the Activity of Transcription Factor Nrf2 to Protect Pancreatic β-Cells From Streptozotocin-Induced Diabetes in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.01562
Abstract: Chronic hyperglycemia and unusually high oxidative stress are the key contributors for diabetes in humans. Since nuclear factor E2-related factor 2 (Nrf2) controls the expression of antioxidant- and detoxification genes, it is hypothesized that targeted… read more here.
Keywords: factor nrf2; nrf2 protect; naringenin; protect pancreatic ... See more keywords
Grapefruit Flavonoid Naringenin Sex-Dependently Modulates Action Potential in an In Silico Human Ventricular Cardiomyocyte Model
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11091672
Abstract: Recent in vitro studies showed that grapefruit (Citrus × paradisi) flavonoid naringenin alters the function of cardiac ion channels. Here, we explored the effect of naringenin on cardiomyocyte action potentials (APs) using a detailed in… read more here.
Keywords: flavonoid naringenin; naringenin; cardiomyocyte; sex ... See more keywords