Dose- and Volume-Limiting Late Toxicity of FLASH Radiotherapy in Cats with Squamous Cell Carcinoma of the Nasal Planum and in Mini Pigs
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DOI: 10.1158/1078-0432.ccr-22-0262
Abstract: Abstract Purpose: The FLASH effect is characterized by normal tissue sparing without compromising tumor control. Although demonstrated in various preclinical models, safe translation of FLASH-radiotherapy stands to benefit from larger vertebrate animal models. Based on… read more here.
Keywords: nasal planum; flash radiotherapy; radiotherapy; mini pigs ... See more keywords
Abnormal keratinocyte differentiation in the nasal planum of Labrador Retrievers with hereditary nasal parakeratosis (HNPK)
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DOI: 10.1371/journal.pone.0225901
Abstract: Hereditary nasal parakeratosis (HNPK) is an inherited disorder described in Labrador Retrievers and Greyhounds. It has been associated with breed-specific variants in the SUV39H2 gene encoding a histone 3 methyltransferase involved in epigenetic silencing. Formalin-fixed… read more here.
Keywords: labrador retrievers; nasal planum; differentiation; hnpk ... See more keywords
Nasal Planum Vasculopathy in a Scottish Terrier Dog Treated with Ciclosporin and Endonasal Stents
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DOI: 10.3390/vetsci5030073
Abstract: A two-year-old, intact female Scottish Terrier presented with one-and-a-half-year history of erosive and ulcerative lesions affecting the nasal planum. Clinical appearance, history, histopathology, and response to therapy were suggestive of a rare vasculopathy of the… read more here.
Keywords: endonasal stents; dog; nasal planum; scottish terrier ... See more keywords
A Retrospective Multicentric Study of Electrochemotherapy in the Treatment of Feline Nasal Planum Squamous Cell Carcinoma
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DOI: 10.3390/vetsci8030053
Abstract: Feline squamous cell carcinoma (SCC) is currently treated with surgery, radiation therapy and electrochemotherapy (ECT). Both the efficacy and/or safety of ECT were evaluated as a sole therapy with bleomycin to treat feline nasal planum… read more here.
Keywords: cell carcinoma; treatment; squamous cell; nasal planum ... See more keywords