Transcriptome sequencing reveals altered ciliogenesis under hypoxia in nasal epithelial cells from chronic rhinosinusitis with nasal polyps
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12168
Abstract: Abstract Background Hypoxia is considered a key factor in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP). However, the specific mechanism driving polypogenesis under hypoxic conditions is unclear. This study aimed to explore hypoxia‐induced… read more here.
Keywords: ciliogenesis; nasal polyps; nasal epithelial; hypoxia ... See more keywords
Adverse events for biologics in patients with CRSwNP: A meta‐analysis
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DOI: 10.1002/clt2.12169
Abstract: Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a common and complex inflammatory disorder in the upper airway. Type 2 inflammation affects the severity of CRSwNP and recurrence of polyps, determining the pharmacotherapy and extent of… read more here.
Keywords: nasal polyps; analysis; adverse events; asthma exacerbation ... See more keywords
Comparative short‐term efficacy of endoscopic sinus surgery and biological therapies in chronic rhinosinusitis with nasal polyps: A network meta‐analysis
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12269
Abstract: Abstract Background To compare the safety and efficacy between endoscopic sinus surgery and different biologics in treating chronic rhinosinusitis with nasal polyps in adults by reviewing the existing clinical trials. Methods Data extraction and risk… read more here.
Keywords: sinus surgery; nasal polyps; endoscopic sinus; efficacy ... See more keywords
Risk factors investigation for different outcomes between unilateral and bilateral chronic rhinosinusitis with nasal polyps patients
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12395
Abstract: Abstract Background Studies involving chronic rhinosinusitis with nasal polyps (CRSwNP) have mostly focused on bilateral cases, making unilateral CRSwNP inadequately recognized. This study examined the differences in clinical characteristics, outcomes, and risk factors for poor… read more here.
Keywords: chronic rhinosinusitis; risk; outcomes unilateral; rhinosinusitis nasal ... See more keywords
Increased serum amyloid A in nasal polyps is associated with systemic corticosteroid insensitivity in patients with chronic rhinosinusitis with nasal polyps: a pilot study
Sign Up to like & getrecommendations! Published in 2017 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-017-4809-z
Abstract: BackgroundSerum amyloid A (SAA) was involved in the pathogenesis of glucocorticoid resistance in lung diseases. However, their association with systemic corticosteroid insensitivity in chronic rhinosinusitis with nasal polyps (CRSwNP) patients remains to be assessed.MethodsThis study… read more here.
Keywords: saa; crswnp patients; corticosteroid insensitivity; nasal polyps ... See more keywords
Different effects of allergic rhinitis on nasal mucosa remodeling in chronic rhinosinusitis with and without nasal polyps
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5195-x
Abstract: BackgroundAllergic rhinitis (AR) has been reported to be associated with chronic rhinosinusitis (CRS). The objective of this study was to investigate the effect of AR on nasal mucosa remodeling in CRS.MethodsPatients were enrolled and divided… read more here.
Keywords: rhinitis; nasal mucosa; mucosa remodeling; crs ... See more keywords
The relationship between endoscopic and radiologic findings and olfactory status of patients with chronic rhinosinusitis with nasal polyps before and after the endoscopic sinus surgery
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5221-z
Abstract: IntroductionThis study was attempted to investigate the relationship between radiologic and endoscopic findings and pre- and post-operative olfactory scores in chronic rhinosinusitis with nasal polyps.Materials and methodsIn this study, 40 patients aged 19–64 years with chronic… read more here.
Keywords: rhinosinusitis nasal; olfactory status; surgery; chronic rhinosinusitis ... See more keywords
Dupilumab: a delayed response in asthmatic and atopic patients treated for chronic rhinosinusitis with nasal polyps
Sign Up to like & getrecommendations! Published in 2024 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-024-08738-2
Abstract: Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is a common disease, which was previously approached with sinus surgery or systemic corticosteroids. The advent of biological therapies radically changed the approach to this disease. On the other… read more here.
Keywords: chronic rhinosinusitis; response; atopic patients; rhinosinusitis nasal ... See more keywords
Neutrophil infiltrates and eosinophil aggregates in chronic rhinosinusitis with nasal polyps and EGPA
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05474-w
Abstract: The histopathological study of inflammatory cells and their tendency to form aggregates in chronic rhinosinusitis with nasal polyps (CRSwNP) has shown promising results in determining the pathogenesis and predicting clinical outcome. Bilateral nasal polyps also… read more here.
Keywords: infiltrates eosinophil; neutrophil infiltrates; rhinosinusitis; nasal polyps ... See more keywords
Budesonide transnasal pulsating nebulization after surgery in chronic rhinosinusitis with nasal polyps.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-00979-6
Abstract: Intranasal corticosteroid drugs are widely used in chronic rhinosinusitis with nasal polyps (CRSwNP). In contrast to classical delivery with nasal pump sprays, pulsating aerosols can deliver significant doses into superior and posterior sinonasal spaces. A… read more here.
Keywords: rhinosinusitis nasal; pulsating nebulization; nasal polyps; chronic rhinosinusitis ... See more keywords
Distinct characteristics of nasal polyps with and without eosinophilia.
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian journal of otorhinolaryngology"
DOI: 10.1016/j.bjorl.2016.01.012
Abstract: INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS… read more here.
Keywords: protein expression; mrna protein; noneosinophilic nps; nasal polyps ... See more keywords