Microtubule-based transport is essential to distribute RNA and nascent protein in skeletal muscle
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26383-9
Abstract: While the importance of RNA localization in highly differentiated cells is well appreciated, basic principles of RNA localization in skeletal muscle remain poorly characterized. Here, we develop a method to detect and quantify single molecule… read more here.
Keywords: skeletal muscle; nascent protein; muscle; transport ... See more keywords
An intrinsically disordered nascent protein interacts with specific regions of the ribosomal surface near the exit tunnel
Sign Up to like & getrecommendations! Published in 2021 at "Communications Biology"
DOI: 10.1038/s42003-021-02752-4
Abstract: The influence of the ribosome on nascent chains is poorly understood, especially in the case of proteins devoid of signal or arrest sequences. Here, we provide explicit evidence for the interaction of specific ribosomal proteins… read more here.
Keywords: protein; exit tunnel; nascent protein; intrinsically disordered ... See more keywords