Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism
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DOI: 10.1038/s41598-019-53346-4
Abstract: Lipotoxicity is a key player in the pathogenesis of nonalcoholic steatohepatitis (NASH), a progressive subtype of nonalcoholic fatty liver disease (NAFLD). In the present study, we combine histological, transcriptional and lipidomic approaches to dissociate common… read more here.
Keywords: nash models; multi technique; metabolism; fed mice ... See more keywords