Phase II trial of natalizumab with corticosteroids as initial treatment of gastrointestinal acute graft-versus-host disease
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DOI: 10.1038/s41409-020-01049-0
Abstract: The α4ß7 integrin is upregulated on naive and memory T cell subsets in patients who subsequently develop gastrointestinal (GI) acute GVHD. Natalizumab (Tysabri®, Biogen Inc.) acts against the α4 subunit that mediates homing of lymphocytes… read more here.
Keywords: acute; initial treatment; gastrointestinal acute; corticosteroids initial ... See more keywords