Microbial production of nattokinase: current progress, challenge and prospect
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DOI: 10.1007/s11274-017-2253-2
Abstract: Nattokinase (EC 3.4.21.62) is a profibrinolytic serine protease with a potent fibrin-degrading activity, and it has been produced by many host strains. Compared to other fibrinolytic enzymes (urokinase, t-PA and streprokinase), nattokinase shows the advantages… read more here.
Keywords: nattokinase; progress challenge; nattokinase production; production ... See more keywords
Stepwise modifications of genetic parts reinforce the secretory production of nattokinase in Bacillus subtilis
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DOI: 10.1111/1751-7915.13298
Abstract: Nattokinase (NK) is an important serine‐protease with direct fibrinolytic activity involving the prevention of cardiovascular disease as an antithrombotic agent. Dozens of studies have focused on the characterization of intrinsic novel promoters and signal peptides… read more here.
Keywords: nattokinase; production; secretory; bacillus subtilis ... See more keywords
High-Efficiency Fermentation of Nattokinase by Recombinant PSP2 Using Oyster Protein Hydrolysate as a Substrate
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DOI: 10.3390/foods12061252
Abstract: In recent years, cardiovascular and cerebrovascular diseases have been the focus of several studies. In this study, oyster protein hydrolysate was produced via enzyme hydrolysis and used as a fermentation substrate to ferment recombinant strain… read more here.
Keywords: nattokinase; oyster protein; protein hydrolysate; substrate ... See more keywords
Production of Nattokinase from Bacillus subtilis - optimization and purification by liquid-liquid extraction
Sign Up to like & getrecommendations! Published in 2017 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2017.00339.0
Abstract: Nattokinase is an enzyme with thrombolytic activity that finds a wide range of function in cardiovascular diseases prevention and many biomedical applications. In this study, Bacillus subtilis was isolated and identified from soil and screened… read more here.
Keywords: nattokinase; production; production nattokinase; liquid extraction ... See more keywords