Site-Selective Synthesis of C-17 Ester Derivatives of Natural Andrographolide for Evaluation as a Potential Anticancer Agent
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DOI: 10.1021/acsomega.3c00036
Abstract: A library of 57 compounds of natural andrographolide was designed, synthesized, and screened for in vitro studies against four human cancer cell lines: A594, PC-3, MCF-7, and HCT-116. Most of the synthesized compounds displayed better… read more here.
Keywords: natural andrographolide; cell; site selective; synthesis ester ... See more keywords