Detection of circulating natural antibodies against CD25, MUC1, and VEGFR1 for early diagnosis of non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12878
Abstract: We previously demonstrated that a deficiency of natural antibodies against CD25, Mucin 1 (MUC1), and vascular endothelial growth factor receptor 1 (VEGFR1) could contribute to high risk of non‐small cell lung cancer (NSCLC). This study… read more here.
Keywords: muc1 vegfr1; natural antibodies; cd25 muc1; combination ... See more keywords
Natural Antibodies: Next Steps Toward Translational Investigation.
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DOI: 10.1007/978-1-4939-7180-0_1
Abstract: Natural antibodies have diverse functions in maintaining immune homeostasis and in the regulation of autoimmune response. Yet there might be other important functions of natural antibodies for human medicine such as the ability of natural… read more here.
Keywords: toward translational; next steps; translational investigation; natural antibodies ... See more keywords
IgA natural antibodies are produced following T-cell independent B-cell activation following stroke
Sign Up to like & getrecommendations! Published in 2021 at "Brain, behavior, and immunity"
DOI: 10.1016/j.bbi.2020.09.014
Abstract: Up to 30% of stroke patients experience cognitive decline within one year of their stroke. There are currently no FDA-approved drugs that can prevent post-stroke cognitive decline, in part due to a poor understanding of… read more here.
Keywords: activation following; following stroke; natural antibodies; iga pcs ... See more keywords
Transfer of natural auto-antibodies via egg yolk in chickens divergently selected for natural antibodies binding keyhole limpet hemocyanin.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2019.103466
Abstract: Barcodes of natural auto-antibody (NAAb) profiles based on staining intensity of isotypes binding numbers of self-(tissue) antigen fragments were suggested as parameters for immune diversity, and related to genetic background and health status in man,… read more here.
Keywords: auto; natural auto; yolk; divergently selected ... See more keywords
Abstract LB-300: Natural antibodies to non-human glycans Neu5Gc and alpha-gal correlate with outcome of high-risk neuroblastoma patients treated with dinutuximab on COG ANBL0032 and ANBL0931
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-lb-300
Abstract: Immunotherapy with ch14.18 (dinutuximab) has significantly improved the survival of high-risk neuroblastoma patients, though late relapses and allergic reaction remain concerning. N-glycolylneuraminic acid (Neu5Gc) and galactose alpha-1,3-galactose (α-gal) are glycans present in most mammals except… read more here.
Keywords: neuroblastoma patients; high risk; natural antibodies; risk neuroblastoma ... See more keywords
NATURAL AB0 ANTIBODIES IN MOKSHA AND ERZYA ETHNIC GROUPS OF THE MORDOVIA REPUBLIC
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DOI: 10.33396/1728-0869-2020-8-26-32
Abstract: The study of natural antibodies as a function of maintaining immunological homeostasis from the position of physiological adaptation of a population is one of the goals of population physiology. The aim is to study natural… read more here.
Keywords: moksha erzya; ab0; erzya ethnic; natural antibodies ... See more keywords
Further analysis of natural antibodies against ischemic stroke
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DOI: 10.3389/fneur.2023.1130748
Abstract: Background Our previous study revealed that circulating levels of IgG natural antibodies (NAbs) for vascular endothelial growth factor receptor 1 (VEGFR1) were significantly decreased in patients with arteriosclerosis compared with control subjects. To enhance the… read more here.
Keywords: natural antibodies; il6 il8; combination; analysis ... See more keywords
Human Natural Antibodies to Mammalian Carbohydrate Antigens as Unsung Heroes Protecting against Past, Present, and Future Viral Infections
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DOI: 10.3390/antib9020025
Abstract: Human natural antibodies to mammalian carbohydrate antigens (MCA) bind to carbohydrate-antigens synthesized in other mammalian species and protect against zoonotic virus infections. Three such anti-MCA antibodies are: (1) anti-Gal, also produced in Old-World monkeys and… read more here.
Keywords: antibodies mammalian; mammalian carbohydrate; human natural; carbohydrate ... See more keywords
Chimeric Peptides from Californiconus californicus and Heterodontus francisci with Antigen-Binding Capacity: A Conotoxin Scaffold to Create Non-Natural Antibodies (NoNaBodies)
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DOI: 10.3390/toxins15040269
Abstract: Research into various proteins capable of blocking metabolic pathways has improved the detection and treatment of multiple pathologies associated with the malfunction and overexpression of different metabolites. However, antigen-binding proteins have limitations. To overcome the… read more here.
Keywords: natural antibodies; capacity; antigen binding; non natural ... See more keywords
The Abrogation of Phosphorylation Plays a Relevant Role in the CCR5 Signalosome Formation with Natural Antibodies to CCR5
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DOI: 10.3390/v10010009
Abstract: The exposure to CCR5 (CC chemokine receptor 5) specific natural antibodies in vitro produces a Class B β-arrestin2-dependent CCR5 retention with the aid of ERK1, due to the formation of a CCR5 signalosome, which remains… read more here.
Keywords: abrogation phosphorylation; ccr5 signalosome; formation; natural antibodies ... See more keywords
Redefining innate natural antibodies as important contributors to anti-tumor immunity
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DOI: 10.7554/elife.69713
Abstract: Myeloid, T, and NK cells are key players in the elimination phase of cancer immunoediting, also referred to as cancer immunosurveillance. However, the role of B cells and NAbs, which are present prior to the… read more here.
Keywords: anti tumor; mice; innate natural; natural antibodies ... See more keywords