Increased peak detection accuracy in over-dispersed ChIP-seq data with supervised segmentation models
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DOI: 10.1186/s12859-021-04221-5
Abstract: Background Histone modification constitutes a basic mechanism for the genetic regulation of gene expression. In early 2000s, a powerful technique has emerged that couples chromatin immunoprecipitation with high-throughput sequencing (ChIP-seq). This technique provides a direct… read more here.
Keywords: chip seq; detection; natural assumptions; segmentation models ... See more keywords