Discovery of natural berberine-derived nitroimidazoles as potentially multi-targeting agents against drug-resistant Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Science China Chemistry"
DOI: 10.1007/s11426-017-9169-4
Abstract: A series of natural berberine-derived nitroimidazoles as novel antibacterial agents were designed, synthesized and characterized by nuclear magnetic resonance (NMR), infrared spectra (IR), and high resolution mass spectra (HRMS) spectra. The antimicrobial evaluation showed that… read more here.
Keywords: berberine derived; drug; drug resistant; natural berberine ... See more keywords
Natural Berberine-Hybridized Benzimidazoles as Novel Unique Bactericides against Staphylococcus aureus.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.1c02545
Abstract: Natural berberine-hybridized benzimidazoles as potential antibacterial agents were constructed to treat Staphylococcus aureus infection in the livestock industry. Bioassay showed that some new berberine-benzimidazole hybrids exhibited potent antibacterial efficacies, especially, the 2,4-dichlorobenzyl derivative 7d not… read more here.
Keywords: benzimidazoles novel; staphylococcus aureus; hybridized benzimidazoles; berberine hybridized ... See more keywords
Natural Berberine-Based Chinese Herb Medicine Assembled Nanostructures with Modified Antibacterial Application.
Sign Up to like & getrecommendations! Published in 2019 at "ACS nano"
DOI: 10.1021/acsnano.9b01346
Abstract: The abuse of traditional antibiotics has caused a series of health problems including antimicrobial resistance, which threatens human health. Therefore, searching for broad sources of antimicrobial agents and developing multidimensional strategies to combat bacterial infections… read more here.
Keywords: medicine; chinese herb; self; natural berberine ... See more keywords