Surgical‐Adjuvant Hydrogel of Full‐Natural Bioactive Compounds from Chinese Medicine for Enhanced Traumatic Brain Injury Therapy by Inhibiting Complement Activation
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202508893
Abstract: Complement activation drives inflammatory cascades that exacerbate secondary injuries in both acute traumatic brain injury (TBI) and postsurgical complications, yet remains clinically unaddressed by timely interventions. Here, a surgical‐adjuvant hydrogel platform (AG‐gel) is engineered through… read more here.
Keywords: activation; adjuvant hydrogel; medicine; surgical adjuvant ... See more keywords
Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications.
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DOI: 10.1002/open.202500469
Abstract: Natural bioactive compounds derived from plants, microbes, and marine organisms represent a rich and diverse reservoir of structurally complex molecules with a broad spectrum of biological activities. This review comprehensively explores the chemical diversity of… read more here.
Keywords: bioactive compounds; chemical diversity; comprehensive insights; nanotechnology ... See more keywords
Targeting molecular pathways in cancer stem cells by natural bioactive compounds
Sign Up to like & getrecommendations! Published in 2018 at "Pharmacological Research"
DOI: 10.1016/j.phrs.2018.08.006
Abstract: ABSTRACT Cancer Stem Cells (CSCs) or Tumor‐Initiating Cells (TICs) are a small sub‐population of cells within the tumor, able to give chemio‐ and radio‐resistance and cause the onset of metastasis and the presence of relapses;… read more here.
Keywords: cancer stem; natural bioactive; bioactive compounds; molecular pathways ... See more keywords
Natural Bioactive Compounds Solanesol and Chlorogenic Acid Assembled Nanomicelles for Alzheimer's Disease Therapy.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.4c22621
Abstract: Solanesol (Sol) and chlorogenic acid (CHA) are naturally active compounds. Sol exhibits a significant free radical absorption ability and strong antioxidant activity. CHA, a typical phenolic acid, exhibits excellent anticancer, anti-inflammation, and antibacterial properties. Herein,… read more here.
Keywords: alzheimer disease; chlorogenic acid; nanomicelles spk; natural bioactive ... See more keywords
Natural Bioactive Molecules as Neuromedicines for the Treatment/Prevention of Neurodegenerative Diseases
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DOI: 10.1021/acsomega.2c06098
Abstract: The brain is vulnerable to different types of stresses, particularly oxidative stress as a result of oxygen requirements/utilization in the body. Large amounts of unsaturated fatty acids present in the brain increase this vulnerability. Neurodegenerative… read more here.
Keywords: molecules neuromedicines; brain; neuromedicines treatment; natural bioactive ... See more keywords
Potential application of natural bioactive compounds as skin‐whitening agents: A review
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.15437
Abstract: Melanin is a skin pigment that gives color to the skin, hair, and eyes. The accumulation or over production of melanin can lead to aesthetic problems as well as serious diseases associated with hyperpigmentation. Skin… read more here.
Keywords: compounds skin; bioactive compounds; application natural; natural bioactive ... See more keywords
Review on Natural Bioactive Products as Radioprotective Therapeutics :Present & Past Perspective.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201023666220110104645
Abstract: Among conventional treatment methodologies, surgery, hyperthermia, radiation, and chemotherapy have become integral components of treatment for most cancers. Radiation therapy in the treatment of many malignancies is always the better choice over surgery and chemotherapy.… read more here.
Keywords: review natural; radiation; natural bioactive; treatment ... See more keywords
Nanomaterials of natural bioactive compounds for wound healing: Novel drug delivery approach.
Sign Up to like & getrecommendations! Published in 2021 at "Current drug delivery"
DOI: 10.2174/1567201818666210729103712
Abstract: Wound healing is biological phenomenon of the body involving sequential biochemical processes that are primarily involved in restoring the cellular integrity of the organ. The market related to wound-care products has extensively been expanded and… read more here.
Keywords: wound healing; drug delivery; natural bioactive; bioactive agents ... See more keywords
Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220330011255
Abstract: The coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms.… read more here.
Keywords: compounds medicinal; bioactive compounds; antibacterial drugs; plants antibacterial ... See more keywords
Natural Bioactive Compounds, Vegetal Extracts and Modern Pharmaceutical Formulations: New Insights into the Anti-Cancer Mechanism of Action.
Sign Up to like & getrecommendations! Published in 2020 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/187152062015200911152012
Abstract: The fact that cancer is the greatest challenge of the medicine of the twenty-first century is undebatable. Moreover it represent a hot topic not only in the medico-pharmaceutical research but scientist belonging to other different… read more here.
Keywords: natural compounds; natural bioactive; chemistry; bioactive compounds ... See more keywords
Natural bioactive compounds modified with mesenchymal stem cells: new hope for regenerative medicine
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2025.1446537
Abstract: Mesenchymal stem cells (MSCs) have the potential to differentiate into various cell types, providing important sources of cells for the development of regenerative medicine. Although MSCs have various advantages, there are also various problems, such… read more here.
Keywords: bioactive compounds; mesenchymal stem; regenerative medicine; stem cells ... See more keywords