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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27196412
Abstract: In designing effective siRNAs for a specific mRNA target, it is critically important to have predictive models for the potency of siRNAs. None of the published methods characterized the chemical structures of individual nucleotides constituting…
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Keywords:
cheminformatics modeling;
chemically modified;
gene silencing;
natural chemically ... See more keywords