BPTF inhibits NK cell activity and the abundance of natural cytotoxicity receptor co-ligands.
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17834
Abstract: Using syngeneic BALB/c mouse breast cancer models, we show that the chromatin remodeling subunit bromodomain PHD finger transcription factor (BPTF) suppresses natural killer (NK) cell antitumor activity in the tumor microenvironment (TME). In culture, BPTF… read more here.
Keywords: bptf; cell activity; natural cytotoxicity; cytotoxicity receptor ... See more keywords
The Natural Cytotoxicity Receptor NKp44 (NCR2, CD336) Is Expressed on the Majority of Porcine NK Cells Ex Vivo Without Stimulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.767530
Abstract: Natural killer (NK) cells have been studied extensively in humans and mice for their vital role in the vertebrate innate immune system. They are known to rapidly eliminate tumors or virus infected cells in an… read more here.
Keywords: porcine cells; cytotoxicity; porcine; nkp44 ncr2 ... See more keywords