Curcumin: A natural derivative with antibacterial activity against Clostridium difficile.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2019.10.005
Abstract: OBJECTIVES The rapid emergence of hypervirulent C. difficile isolates and the paucity of effective anticlostridial antibiotics call for extensive research to identify new treatment options. The objective of the present study was to test the… read more here.
Keywords: derivative antibacterial; difficile; antibacterial activity; curcumin natural ... See more keywords
Molecular modelling and structure-activity relationship of a natural derivative of o-hydroxybenzoate as a potent inhibitor of dual NSP3 and NSP12 of SARS-CoV-2: in silico study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2026818
Abstract: Abstract The nsp3 macrodomain and nsp12 (RdRp) enzymes are strongly implicated in the virulent regulation of the host immune response and viral replication of SARS-CoV-2, making them plausible therapeutic targets for mitigating infectivity. Remdesivir remains… read more here.
Keywords: structure; hydroxybenzoate; inhibitor; natural derivative ... See more keywords