Natural-derived COX-2 inhibitors as Anticancer Drugs: A Review of Their Structure Diversity and Mechanism of Action.
Sign Up to like & getrecommendations! Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1389450123666220516153915
Abstract: Cyclooxygenase-2 (COX-2) is a key-type enzyme playing a crucial role in cancer development, making it a target of high interest for drug designers. In the last two decades, numerous selective COX-2 inhibitors have been approved… read more here.
Keywords: cox inhibitors; structure; cox; natural derived ... See more keywords
The antibacterial activity of natural-derived flavonoids.
Sign Up to like & getrecommendations! Published in 2022 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026622666220221110506
Abstract: Flavonoids, a wide variety of phenolic secondary metabolites, are found in almost all plant families in the leaves, stems, roots, flowers, and seeds. Flavonoids could exert antibacterial activity via damaging the cytoplasmic membrane, inhibiting energy… read more here.
Keywords: antibacterial activity; derived flavonoids; chemistry; activity natural ... See more keywords
Natural-Derived Molecules as a Potential Adjuvant in Chemotherapy: Normal Cell Protectors and Cancer Cell Sensitizers.
Sign Up to like & getrecommendations! Published in 2021 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520621666210623104227
Abstract: BACKGROUND Cancer is a global threat to humans and a leading cause of death worldwide. Cancer treatment includes, among other things, the use of chemotherapeutic agents, compounds that are vital for treating and preventing cancer.… read more here.
Keywords: natural derived; chemotherapeutic agents; cancer; cell ... See more keywords
Potential of natural flavonols and flavanones in the treatment of ulcerative colitis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2023.1120616
Abstract: Ulcerative colitis (UC) is an inflammatory bowel disease generally characterized by chronic, persistent, recurrent, and non-specific ulcers of the intestine. Its main clinical manifestations include abdominal pain, diarrhea, and bloody stools. This disease is difficult… read more here.
Keywords: flavonols flavanones; natural flavonols; natural derived; ulcerative colitis ... See more keywords