Design, Semisynthesis, and Estrogenic Activity of Lignan Derivatives from Natural Dibenzylbutyrolactones
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DOI: 10.3390/ph15050585
Abstract: Based on molecular docking studies on the ERα, a series of lignan derivatives (3–16) were designed and semisynthesized from the natural dibenzylbutyrolactones bursehernin (1) and matairesinol dimethyl ether (2). To examine their estrogenic and antiestrogenic… read more here.
Keywords: natural dibenzylbutyrolactones; estrogenic activity; design semisynthesis; lignan derivatives ... See more keywords