In-Silico Screening-Based Discovery of New Natural eEF2K Inhibitors with Neuritogenic Activity.
Sign Up to like & getrecommendations! Published in 2025 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.4c00635
Abstract: Eukaryotic elongation factor 2 kinase (eEF2K), an atypical Ser/Thr-protein kinase that regulates neuronal protein synthesis homeostasis via an inhibitory phosphorylation of eEF2, has emerged as a promising therapeutic target for several diseases, including Alzheimer's disease… read more here.
Keywords: natural eef2k; eef2k inhibitors; eef2k; protein ... See more keywords