Characterization of Natural IgM Antibodies Recognizing Oxidation-Specific Epitopes on Circulating Microvesicles.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7180-0_11
Abstract: Natural IgM antibodies specific for oxidation-specific epitopes (OSEs) have been found to bind to circulating microvesicles (MVs), also known as microparticles. This chapter describes how endogenous natural IgM antibodies bound to circulating MV subsets can… read more here.
Keywords: natural igm; oxidation specific; igm antibodies; specific epitopes ... See more keywords
Plasmablasts induced by chitosan oligosaccharide secrete natural IgM to enhance the humoral immunity in grass carp.
Sign Up to like & getrecommendations! Published in 2022 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2021.119073
Abstract: Chitosan oligosaccharide (COS) is an attractive immunopotentiator capable of driving humoral immunity in vertebrates, but its cellular and molecular mechanisms still require elucidation. In this study, COS induced the proliferation and differentiation of splenic IgM+… read more here.
Keywords: grass carp; humoral immunity; natural igm; chitosan oligosaccharide ... See more keywords
Natural IgM antibodies in the immune defence against neoehrlichiosis
Sign Up to like & getrecommendations! Published in 2017 at "Infectious Diseases"
DOI: 10.1080/23744235.2017.1347815
Abstract: Abstract Background: Neoehrlichiosis is an infectious disease caused by the tick-borne bacterium “Candidatus Neoehrlichia mikurensis”. Splenectomy and rituximab therapies are risk factors for severe neoehrlichiosis. Our aim was to examine if neoehrlichiosis patients had low… read more here.
Keywords: natural igm; immune defence; igm antibodies; neoehrlichiosis ... See more keywords
Role of Natural IgM and IgM Induced Bregs in Preventing Ischemia Induced Innate Inflammation and Acute Kidney Injury
Sign Up to like & getrecommendations! Published in 2019 at "Nephron"
DOI: 10.1159/000501639
Abstract: Ischemic acute kidney injury (AKI) is predominantly mediated by the innate inflammatory response to damage-associated molecular patterns released during the reperfusion phase of the ischemic event. In this study, we show that pre-emptive IgM infusions… read more here.
Keywords: natural igm; kidney injury; igm; acute kidney ... See more keywords
Natural IgM and TLR Agonists Switch Murine Splenic Pan-B to “Regulatory” Cells That Suppress Ischemia-Induced Innate Inflammation via Regulating NKT-1 Cells
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00974
Abstract: Natural IgM anti-leukocyte autoantibodies (IgM-ALAs) inhibit inflammation by several mechanisms. Here, we show that pan-B cells and bone marrow-derived dendritic cells (BMDCs) are switched to regulatory cells when pretreated ex vivo with IgM. B cells… read more here.
Keywords: natural igm; inflammation; regulatory cells; induced regulatory ... See more keywords
Recognition of tumor antigens in 4T1 cells by natural IgM from three strains of mice with different susceptibilities to spontaneous breast cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Oncology letters"
DOI: 10.3892/ol.2016.5427
Abstract: The issue of antibody responses to tumors is potentially important to cancer immunologists. Early detection of cancer represents one of the most promising approaches to reduce the growing cancer burden. Natural immunoglobulin (Ig)M antibodies have… read more here.
Keywords: natural igm; 4t1 cells; antigens 4t1; breast cancer ... See more keywords