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Published in 2018 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2018.07.005
Abstract: In order to find more natural lead-compounds as inhibitors for Cyclooxygenase-2, the essential structural features for human cyclooxygenase-2 inhibitors and 3D-Quantitative structure activity relationship (3D-QSAR) model were carried out based on dataset from three confirmatory…
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Keywords:
cyclooxygenase inhibitors;
lead compounds;
aided identification;
natural lead ... See more keywords
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Published in 2019 at "Environmental science & technology"
DOI: 10.1021/acs.est.8b04191
Abstract: The natural lead concentration of dandelion ( Taraxacum officinale) leaves is estimated to be 0.2 μg/g (dry weight), or 1-3 orders of magnitude below most contemporary measurements of that value for dandelions and other plants.…
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Keywords:
taraxacum officinale;
medicine;
lead levels;
natural lead ... See more keywords
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Published in 2020 at "Molecules"
DOI: 10.3390/molecules25030733
Abstract: Honokiol (2) is a natural bisphenol neolignan showing a variety of biological properties, including antitumor activity. Some studies pointed out 2 as a potential anticancer agent in view of its antiproliferative and pro-apoptotic activity towards…
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Keywords:
bisphenol;
neolignans inspired;
antiproliferative agents;
bisphenol neolignans ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27010265
Abstract: Genistein is a naturally occurring polyphenolic molecule in the isoflavones group which is well known for its neuroprotection. In this review, we summarize the efficacy of genistein in attenuating the effects of memory impairment (MI)…
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Keywords:
design development;
memory impairment;
natural lead;
potential natural ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27030673
Abstract: Cardiovascular disorders (CVDs) are the leading risk factor for death worldwide, and research into the processes and treatment regimens has received a lot of attention. Tilianin is a flavonoid glycoside that can be found in…
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Keywords:
development;
cardiovascular disorders;
drug;
natural lead ... See more keywords