Articles with "natural mutations" as a keyword



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Discovering interrelated natural mutations of efflux pump KmrA from Klebsiella pneumoniae that confer increased multidrug resistance

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Published in 2022 at "Protein Science"

DOI: 10.1002/pro.4323

Abstract: Klebsiella pneumoniae is a notorious pathogen that can cause multiorgan infections, which is difficult to treat mainly due to the widely distributed efflux pumps. Our previous research discovered the upregulation of efflux pump KmrA conferred… read more here.

Keywords: pneumoniae; klebsiella pneumoniae; natural mutations; resistance ... See more keywords
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The impact of receptor-binding domain natural mutations on antibody recognition of SARS-CoV-2

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Published in 2021 at "Signal Transduction and Targeted Therapy"

DOI: 10.1038/s41392-021-00536-0

Abstract: Dear Editor, The ongoing COVID-19 pandemic has resulted in over 25.0 million confirmed cases and over 840,000 deaths globally. As the third severe respiratory disease outbreak caused by the coronavirus, COVID-19 has led to much… read more here.

Keywords: escape; antibody; rbd; natural mutations ... See more keywords