Advances in natural small molecules on pretranslational regulation of gluconeogenesis.
Sign Up to like & getrecommendations! Published in 2023 at "Drug development research"
DOI: 10.1002/ddr.22053
Abstract: Different tissues and organs coordinate to keep glucose levels at homeostasis. However, excessive gluconeogenesis in patients with type 2 diabetes mellitus increases blood glucose and causes dysregulation of homeostasis, which easily induces various diseases. Therefore,… read more here.
Keywords: regulation gluconeogenesis; molecules pretranslational; pretranslational regulation; natural small ... See more keywords
Nanomedicine-cum-Carrier by Co-assembly of Natural Small Products for Synergistic Enhanced Antitumor with Tissues Protective Actions.
Sign Up to like & getrecommendations! Published in 2020 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.0c12641
Abstract: The application of natural small products with self-assembly characteristics in drug-delivery system is attractive for biomedical applications, because of its inherent biological safety and pharmacological activity, and there is no complex structural modification process. However,… read more here.
Keywords: small products; cum carrier; drug; natural small ... See more keywords
Natural Small Biological Molecule Based Supramolecular Bioadhesives with Innate Photothermal Antibacterial Capability for Nonpressing Hemostasis and Effective Wound Healing.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c17415
Abstract: Bioadhesives with immediate wound closure, efficient hemostasis, and antibacterial properties that can well integrate with tissue are urgently needed in wound management. Natural small biological molecule based bioadhesives hold great promise for manipulating wound healing… read more here.
Keywords: biological molecule; wound healing; natural small; molecule based ... See more keywords
Potential Natural Small Molecular Compounds for the Treatment of Chronic Obstructive Pulmonary Disease: An Overview
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.821941
Abstract: Chronic obstructive pulmonary disease (COPD) is one of the major diseases threatening human life and health. According to the report released by the World Health Organization (WHO) in 2020, COPD has become the third leading… read more here.
Keywords: natural small; obstructive pulmonary; chronic obstructive; molecular compounds ... See more keywords
A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.956154
Abstract: The homeostasis of eukaryotic cells is inseverable of that of the endoplasmic reticulum (ER). The main function of this organelle is the synthesis and folding of a significant portion of cellular proteins, while also being… read more here.
Keywords: molecule inhibitors; endoplasmic reticulum; stress; small molecule ... See more keywords
Research Progress of Natural Small-Molecule Compounds Related to Tumor Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27072128
Abstract: Tumor differentiation is a therapeutic strategy aimed at reactivating the endogenous differentiation program of cancer cells and inducing cancer cells to mature and differentiate into other types of cells. It has been found that a… read more here.
Keywords: differentiation; small molecule; molecule compounds; natural small ... See more keywords
Natural Small Molecules in Gastrointestinal Tract and Associated Cancers: Molecular Insights and Targeted Therapies
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27175686
Abstract: Gastric cancer is one of the most common cancers of the gastrointestinal tract. Although surgery is the primary treatment, serious maladies that dissipate to other parts of the body may require chemotherapy. As there is… read more here.
Keywords: stomach cancer; natural small; small molecules; cancer ... See more keywords
Discovery of Natural Small Molecules Promoting Collagen Secretion by High-Throughput Screening in Caenorhabditis elegans
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27238361
Abstract: Advancing approaches for drug screening are in great demand to explore natural small molecules that may play important roles in collagen biogenesis, secretion, and assembly, which may find novel lead compounds for treating collagen-related diseases… read more here.
Keywords: natural small; col; collagen; caenorhabditis elegans ... See more keywords