Identification of naturally processed Zika virus peptides by mass spectrometry and validation of memory T cell recall responses in Zika convalescent subjects
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DOI: 10.1371/journal.pone.0252198
Abstract: Once an obscure pathogen, Zika virus (ZIKV) has emerged as a significant global public health concern. Several studies have linked ZIKV infection in pregnant women with the development of microcephaly and other neurological abnormalities, emphasizing… read more here.
Keywords: memory cell; mass spectrometry; zikv; naturally processed ... See more keywords
Personalized adoptive immunotherapy for patients with EBV-associated tumors and complications: Evaluation of novel naturally processed and presented EBV-derived T-cell epitopes
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DOI: 10.18632/oncotarget.23531
Abstract: Morbidity and mortality of immunocompromised patients are increased by primary infection with or reactivation of Epstein-Barr virus (EBV), possibly triggering EBV+ post-transplant lymphoproliferative disease (PTLD). Adoptive transfer of EBV-specific cytotoxic T cells (EBV-CTLs) promises a… read more here.
Keywords: ebv; ebv specific; immunotherapy; naturally processed ... See more keywords
Identification of Naturally Processed Epitope Region Using Artificial APC Expressing a Single HLA Class I Allotype and mRNA of HCMV pp65 Antigen Fragments
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DOI: 10.3390/vaccines10050787
Abstract: Recently, long synthetic peptides or in silico-predicted epitope peptides have been used to identify T cell epitopes, but these approaches may not be suitable for investigating naturally processed epitopes. Here, mRNAs, including fragments or predicted… read more here.
Keywords: naturally processed; pp65 antigen; hla; epitope ... See more keywords