Lessons from nature: Structural studies and drug design driven by a homologous surrogate from invertebrates, AChBP
Sign Up to like & getrecommendations! Published in 2020 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2020.108108
Abstract: It has been almost 20 years since the discovery and crystallization of a structural surrogate, the Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP), comprising the extracellular domain of the nicotinic acetylcholine receptors (nAChRs). Structural characterization of… read more here.
Keywords: studies drug; surrogate; structural studies; lessons nature ... See more keywords
Nature of the structural symmetries associated with hybrid improper ferroelectricity in Ca3X2O7(X=Mnand Ti)
Sign Up to like & getrecommendations! Published in 2019 at "Physical Review B"
DOI: 10.1103/physrevb.99.224105
Abstract: In hybrid improper ferroelectric systems, polarization arises from the onset of successive nonpolar lattice modes. In this work, measurements and modeling were performed to determine the spatial symmetries of the phases involved in the transitions… read more here.
Keywords: ferroelectricity; symmetries associated; ca3x2o7; structural symmetries ... See more keywords