Molecular Dynamics Simulations of Ion Permeation in Human Voltage-Gated Sodium Channels
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DOI: 10.1021/acs.jctc.2c00990
Abstract: The recent determination of cryo-EM structures of voltage-gated sodium (Nav) channels has revealed many details of these proteins. However, knowledge of ionic permeation through the Nav pore remains limited. In this work, we performed atomistic… read more here.
Keywords: voltage gated; nav; molecular dynamics; cryo ... See more keywords
Contribution of voltage-gated sodium channel β-subunits to cervical cancer cells metastatic behavior
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DOI: 10.1186/s12935-019-0757-6
Abstract: BackgroundVoltage-gated sodium (NaV) channels are heteromeric proteins consisting of a single pore forming α-subunit associated with one or two auxiliary β-subunits. These channels are classically known for being responsible of action potential generation and propagation… read more here.
Keywords: cervical cancer; expression; nav; ceca ... See more keywords