Activity-dependent formation and location of voltage-gated sodium channel clusters at a CNS nerve terminal during postnatal development.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of neurophysiology"
DOI: 10.1152/jn.00617.2016
Abstract: In auditory pathways, the precision of action potential (AP) propagation depends on axon myelination and high densities of voltage-gated Na (Nav) channels clustered at nodes of Ranvier. Changes in Nav channel expression at the heminode,… read more here.
Keywords: nerve terminal; channel clusters; channel; nav channel ... See more keywords
Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na+ Channel 1.6 Enables Isoform-Selective Modulation.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of molecular sciences"
DOI: 10.3390/ijms222413541
Abstract: Voltage-gated Na+ (Nav) channels are the primary molecular determinant of the action potential. Among the nine isoforms of the Nav channel α subunit that have been described (Nav1.1-Nav1.9), Nav1.1, Nav1.2, and Nav1.6 are the primary… read more here.
Keywords: channel; nav channel; modulation; interaction site ... See more keywords