NaV1.1 haploinsufficiency impairs glutamatergic and GABAergic neuron function in the thalamus
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DOI: 10.1016/j.nbd.2022.105672
Abstract: Thalamocortical network dysfunction contributes to seizures and sleep deficits in Dravet syndrome (DS), an infantile epileptic encephalopathy, but the underlying molecular and cellular mechanisms remain elusive. DS is primarily caused by mutations in the SCN1A… read more here.
Keywords: nav1 haploinsufficiency; thalamus; neuron; function ... See more keywords