Nav1.6 promotes inflammation and neuronal degeneration in a mouse model of multiple sclerosis
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DOI: 10.1186/s12974-019-1622-1
Abstract: BackgroundIn multiple sclerosis (MS) and in the experimental autoimmune encephalomyelitis (EAE) model of MS, the Nav1.6 voltage-gated sodium (Nav) channel isoform has been implicated as a primary contributor to axonal degeneration. Following demyelination Nav1.6, which… read more here.
Keywords: nav1 promotes; model; multiple sclerosis; axonal degeneration ... See more keywords