Ablation of SigH+ pDCs in B6.Nba2 mice prevents lupus-like disease development only if started before disease is fully established
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DOI: 10.1177/09612033221127561
Abstract: Systemic lupus erythematosus is characterized by hyper-activation of the immune system, multi-organ inflammation, and end-organ damage. Type I interferons (IFN-I) have been strongly implicated a role in disease etiology as has the main IFN-I-producing cell… read more here.
Keywords: disease; disease development; ablation; nba2 mice ... See more keywords