Introducing Conformational Restraints on 25CN-NBOH: A Selective 5-HT2A Receptor Agonist.
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DOI: 10.1021/acsmedchemlett.3c00014
Abstract: The N-benzylphenethylamines (NBOMes) are a class of ligands from which compounds with impressive selectivity for the serotonin 2A receptor (5-HT2AR) over the closely related serotonin 2C receptor (5-HT2CR) have emerged. These include 4-(2-((2-hydroxybenzyl)amino)ethyl)-2,5-dimethoxybenzonitrile (25CN-NBOH, 1)… read more here.
Keywords: nboh selective; restraints 25cn; conformational restraints; receptor ... See more keywords