Identification of permissive amber suppression sites for efficient non-canonical amino acid incorporation in mammalian cells
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DOI: 10.1093/nar/gkab132
Abstract: Abstract The genetic code of mammalian cells can be expanded to allow the incorporation of non-canonical amino acids (ncAAs) by suppressing in-frame amber stop codons (UAG) with an orthogonal pyrrolysyl-tRNA synthetase (PylRS)/tRNAPylCUA (PylT) pair. However,… read more here.
Keywords: incorporation; ncaa incorporation; non canonical; canonical amino ... See more keywords