Morroniside alleviates lipopolysaccharide-induced inflammatory and oxidative stress in inflammatory bowel disease by inhibiting NLRP3 and NF-κB signaling pathways.
Sign Up to like & getrecommendations! Published in 2022 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v50i6.674
Abstract: OBJECTIVE To investigate the effects of morroniside on inflammatory and oxidative stress in lipopolysaccharide (LPS)-induced inflammatory bowel disease (IBD) cell model. METHODS NCM460 cells were treated with 2-, 5-, or 10-μg/mL LPS for 24 h… read more here.
Keywords: stress; induced inflammatory; oxidative stress; lps induced ... See more keywords
Multi-Omics Reveal Additive Cytotoxicity Effects of Aflatoxin B1 and Aflatoxin M1 toward Intestinal NCM460 Cells
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DOI: 10.3390/toxins14060368
Abstract: Aflatoxin B1 (AFB1) is a common crop contaminant, while aflatoxin M1 (AFM1) is implicated in milk safety. Humans are likely to be simultaneously exposed to AFB1 and AFM1; however, studies on the combined interactive effects… read more here.
Keywords: cell; multi omics; afb1 afm1; ncm460 cells ... See more keywords
Integrated Metabolomics and Lipidomics Analysis Reveals Lipid Metabolic Disorder in NCM460 Cells Caused by Aflatoxin B1 and Aflatoxin M1 Alone and in Combination
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DOI: 10.3390/toxins15040255
Abstract: Aflatoxin B1 (AFB1) and aflatoxin M1 (AFM1) are universally found as environmental pollutants. AFB1 and AFM1 are group 1 human carcinogens. Previous sufficient toxicological data show that they pose a health risk. The intestine is… read more here.
Keywords: metabolism; combination; afb1 afm1; ncm460 cells ... See more keywords