Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4710-1
Abstract: BackgroundSirtuin 2 (SIRT2) is a member of the sirtuin family, nicotinamide adenine dinucleotide+-dependent deacylases, which participates in modulation of cell cycle control, neurodegeneration, and tumorigenesis. SIRT2 expression increases in acute myeloid leukemia blasts. Downregulation of… read more here.
Keywords: leukemic cell; sirt2; cell lines; cell death ... See more keywords