Quantitative omics analyses of NCOA4 deficiency reveal an integral role of ferritinophagy in iron homeostasis of hippocampal neuronal HT22 cells
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DOI: 10.3389/fnut.2023.1054852
Abstract: Introduction Neurons require iron to support their metabolism, growth, and differentiation, but are also susceptible to iron-induced oxidative stress and cytotoxicity. Ferritin, a cytosolic iron storage unit, mediates cellular adaptation to fluctuations in iron delivery.… read more here.
Keywords: hippocampal neuronal; ht22 cells; iron; ncoa4 deficiency ... See more keywords