Basic and editing mechanisms underlying ion transport and regulation in NCX variants.
Sign Up to like & getrecommendations! Published in 2019 at "Cell calcium"
DOI: 10.1016/j.ceca.2019.102131
Abstract: Structure-dynamic analysis of archaeal NCX (NCX_Mj) provided new insights into the underlying mechanisms of ion selectivity, ion-coupled alternating access, ion occlusion, and transport catalysis. This knowledge is relevant, not only for prokaryotic and eukaryotic NCXs,… read more here.
Keywords: ion transport; ca2 binding; ion; ncx variants ... See more keywords
Structure-Based Function and Regulation of NCX Variants: Updates and Challenges
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010061
Abstract: The plasma-membrane homeostasis Na+/Ca2+ exchangers (NCXs) mediate Ca2+ extrusion/entry to dynamically shape Ca2+ signaling/in biological systems ranging from bacteria to humans. The NCX gene orthologs, isoforms, and their splice variants are expressed in a tissue-specific… read more here.
Keywords: structure; ncx variants; regulation ncx; function regulation ... See more keywords