Sequential treatment with aT19 cells generates memory CAR-T cells and prolongs the lifespan of Raji-B-NDG mice.
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DOI: 10.1016/j.canlet.2019.10.022
Abstract: Treatment with chimeric antigen receptor (CAR)-modified T cells targeting CD19 has proved successful in patients with relapsed/refractory B cell malignancies. However, long-term follow-up indicates that remission in a substantial proportion of patients is not sustainable.… read more here.
Keywords: sequential treatment; raji ndg; car cells; ndg mice ... See more keywords