Expanding the Substrate Scope of a Bacterial Nucleotidyltransferase via Allosteric Mutations.
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DOI: 10.1021/acsinfecdis.2c00402
Abstract: Bacterial glycoconjugates, such as cell surface polysaccharides and glycoproteins, play important roles in cellular interactions and survival. Enzymes called nucleotidyltransferases use sugar-1-phosphates and nucleoside triphosphates (NTPs) to produce nucleoside diphosphate sugars (NDP-sugars), which serve as… read more here.
Keywords: nucleotidyltransferase; expanding substrate; ndp sugars; scope bacterial ... See more keywords