NDST3-Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease.
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DOI: 10.1002/advs.202507323
Abstract: Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons (DN) in the substantia nigra and disruption of cellular maintenance. Here, we demonstrate that NDST3-mediated epigenetic reprogramming halts neuronal degeneration… read more here.
Keywords: ndst3; parkinson disease; ndst3 induced; epigenetic reprogramming ... See more keywords
Tubulin deacetylase NDST3 modulates lysosomal acidification: Implications in neurological diseases
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DOI: 10.1002/bies.202200110
Abstract: Neurological diseases (NDs), featured by progressive dysfunctions of the nervous system, have become a growing burden for the aging populations. N‐Deacetylase and N‐sulfotransferase 3 (NDST3) is known to catalyze deacetylation and N‐sulfation on disaccharide substrates.… read more here.
Keywords: neurological diseases; lysosomal acidification; deacetylase; tubulin deacetylase ... See more keywords