Long noncoding RNA NEAT1 decreases polycystic ovary syndrome progression via the modulation of the microRNA‐324‐3p and BRD3 axis
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11893
Abstract: Long noncoding RNA nuclear‐enriched abundant transcript 1 (NEAT1) is believed to be involved in many gynecological and obstetrics disorders. Nevertheless, the role of NEAT1 in polycystic ovary syndrome (PCOS) is scarcely investigated. Our study aimed… read more here.
Keywords: pcos mice; neat1; long noncoding; 324 brd3 ... See more keywords
NEAT1 accelerates the progression of liver fibrosis via regulation of microRNA-122 and Kruppel-like factor 6
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-017-1586-5
Abstract: Long non-coding RNAs (lncRNAs) have been reported to be involved in many important biological processes including proliferation, apoptosis, differentiation, and survival. Recently, nuclear paraspeckle assembly transcript 1 (NEAT1), a novel lncRNA, serves as a crucial… read more here.
Keywords: hsc activation; neat1; mir 122; liver fibrosis ... See more keywords
Knockdown lncRNA NEAT1 regulates the activation of microglia and reduces AKT signaling and neuronal apoptosis after cerebral ischemic reperfusion
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-71411-1
Abstract: Acute cerebral ischaemia may lead to serious consequences, including brain injury caused by uncontrolled reperfusion, which occurs when circulation is re-established. The long non-coding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) plays an important… read more here.
Keywords: knockdown lncrna; apoptosis; neat1; reperfusion ... See more keywords
LncRNA NEAT1 promotes colorectal cancer cell proliferation and migration via regulating glial cell-derived neurotrophic factor by sponging miR-196a-5p
Sign Up to like & getrecommendations! Published in 2018 at "Acta Biochimica et Biophysica Sinica"
DOI: 10.1093/abbs/gmy130
Abstract: Colorectal cancer (CRC) is the one of the most common malignant tumors worldwide. Recent years, widespread long non-coding RNAs (lncRNAs) have been discovered and are known to regulate gene expression in cancers. However, the roles… read more here.
Keywords: proliferation migration; cell proliferation; neat1; mir 196a ... See more keywords
Long noncoding RNA NEAT1 mediates neuronal histone methylation and age-related memory impairment
Sign Up to like & getrecommendations! Published in 2019 at "Science Signaling"
DOI: 10.1126/scisignal.aaw9277
Abstract: Aging-related expression of the lncRNA NEAT1 facilitates epigenetic inhibition of memory formation. On memory and aging It is an unfortunate aspect of aging that memory tends to decline. Butler et al. identified one way by… read more here.
Keywords: long noncoding; hippocampus; neat1; formation ... See more keywords
Bone Mesenchymal Stem Cell-Derived Extracellular Vesicles Containing Long Noncoding RNA NEAT1 Relieve Osteoarthritis
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/5517648
Abstract: Extracellular vesicles (EVs) derived from bone marrow mesenchymal stem cells (BMSCs) possess potentials in modulation of the biological process in various diseases. However, an extensive investigation of the mechanism of BMSC-derived EVs (BMSC-EVs) in osteoarthritis… read more here.
Keywords: extracellular vesicles; neat1; bmsc evs; mir 122 ... See more keywords
The Neat Dance of COVID-19: NEAT1, DANCR, and Co-Modulated Cholinergic RNAs Link to Inflammation
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.590870
Abstract: The COVID-19 pandemic exerts inflammation-related parasympathetic complications and post-infection manifestations with major inter-individual variability. To seek the corresponding transcriptomic origins for the impact of COVID-19 infection and its aftermath consequences, we sought the relevance of… read more here.
Keywords: infection; inflammation; neat1; dancr ... See more keywords
Depletion of LncRNA NEAT1 Rescues Mitochondrial Dysfunction Through NEDD4L-Dependent PINK1 Degradation in Animal Models of Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2020.00028
Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disorder and the main cause of dementia among the elderly worldwide. Unfortunately, the mechanism of AD remains unclear, and no effective therapies are available yet. An increasing… read more here.
Keywords: alzheimer disease; neat1; pink1; lncrna neat1 ... See more keywords